Other Departments: Biochemistry
Degrees: B.A., Colgate University; Ph.D., Emory University
Office Location: Doane Hall of Chemistry C.215
Office Hours: MW 12:30-1:30 pm; T 8:30-10:30 am; F 2-4 pm
Research in the Murphree group focuses mainly on synthetic methodology, particularly through the use of sulfones. For example, the sulfone-based reagent 2,3-dibromo-1-(phenylsulfonyl)-1-propene, or DBP, reacts with 1,3-diketones to form 2,4-disubstituted furans, a structural motif found in some naturally occurring products of biological and industrial interest.
Ongoing projects are exploring the synthetic utility of this methodology, as well as the chemistry of other novel sulfonyl-substituted small molecules.
An additional research interest involves the development of more environmentally benign modifications of classical industrial syntheses through the use of catalytic methods.