July 24, 2015 — Ivelitza Garcia, assistant professor of chemistry and biochemistry at Allegheny College, received a grant of $174,038 from the National Science Foundation in support of her project “Research in Undergraduate Institutions: Catalytic regulation of ribosome processing factors: Investigation of peripheral domain effects on the enzymatic capabilities of the DEAD-box protein Rok1p.”
The grant will provide funding for eight Allegheny students over four years to collaborate with Garcia to investigate how different structural elements within DEAD-box proteins can regulate the activity and initial structural state of a protein model. Understanding the regulation of DEAD-box proteins is of high medical interest since they are often over- or under-expressed in breast, cervical and prostate cancer as well as in T-cell and myeloid leukemia.
One hundred percent of the $174,038 cost of the project will be covered by federal funds through the NSF grant.
Photo: Winnie Wong at work in Ivelitza Garcia’s lab.